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B., Yang, Y., Xu, X

Trends Cancer 10 , 519530 (2024)

Antibiotics profoundly disrupt gut microbiota, transiently reducing IS/pCS production for weeks post-treatment, and phosphate binders such as sevelamer bind IS in the gut, lowering circulating levels independent of microbial production changes

Taking it away from a heavy meal prevents it from being caught up in the complex digestive process of fats and fibers, which could potentially degrade the supplement before it reaches the bloodstream

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